Production Deployment Date for FDA Supplemental Guide v. 2.6 was March 10, 2026

On Tuesday, March 10, 2026, the changes related to the U.S. Food and Drug Administration (FDA) ACE Supplemental Guide (SG) Version 2.6 were deployed to the CBP PRODUCTION environment. 
The SG 2.6 was moved from the DRAFT CHAPTERS: Future Capabilities section to the Implementation Guide Ready for Coding section in the PGA documents section on CBP.gov: ACE Automated Broker Interface (ABI) CBP and Trade Automated Interface Requirements (CATAIR) [ https://www.cbp.gov/trade/automated/catair ] 
Refer to the Change Log in the document for all changes. 
The following FDA documents associated with this deployment will also be updated: FDA ACE Affirmation of Compliance Codes, FDA ACE Affirmation of Compliance Quick Reference, and Industry Quick Reference Guide to the FDA ACE Supplemental Guide. These FDA documents can be found here: Automated Commercial Environment/International Trade Data System (ACE/ITDS) [ https://www.fda.gov/industry/import-systems/automated-commercial-environmentinternational-trade-data-system-aceitds ]
For questions about FDA message set requirements, contact FDA ACE Support at ACE_Support@fda.hhs.gov.
Related Message Number(s): # 66836343, 66347264 and 67780481